visualization

Variant Interaction Analysis (VIA) is an application for identifying genomic variant interactions related with complex diseases. It uses Multifactor Dimensionality Dimension (MDR), a non-parametric statistical method for detecting and characterizing nonlinear interactions. It runs in a singularity container using Apache Spark for distributing the work, Hadoop File System for distributing the data and Apache ZooKeeper for synchronization. It is coded in Python.

Official repository for the contributions to the manuscript "A dataset to reveal 863 different causes of Rett syndrome and lessons learned from data integration".